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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 1
1994 5
1995 6
1996 8
1997 10
1998 18
1999 24
2000 28
2001 33
2002 28
2003 39
2004 41
2005 46
2006 52
2007 65
2008 71
2009 69
2010 68
2011 95
2012 91
2013 106
2014 104
2015 112
2016 90
2017 90
2018 106
2019 96
2020 94
2021 86
2022 72
2023 62
2024 24

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1,631 results

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Page 1
Bone marrow stromal cell antigen 2(BST2) suppresses the migration and invasion of trophoblasts in preeclampsia by downregulating matrix metallopeptidase 2(MMP2).
Jinyu L, Shuying W, Panchan Z, Dan C, Chao C, Xingyu Y, Weiwei C. Jinyu L, et al. Bioengineered. 2022 May;13(5):13174-13187. doi: 10.1080/21655979.2022.2074712. Bioengineered. 2022. PMID: 35635087 Free PMC article.
BST2 knockdown could reverse these effects. MMP2 knockdown could downregulate the invasion capacity of HTR-8/SVneo cells, and MMP2 overexpression reversed these effects. Pearson correlation analysis demonstrated that the expression of MMP2 and BST2 were posit …
BST2 knockdown could reverse these effects. MMP2 knockdown could downregulate the invasion capacity of HTR-8/SVneo cells, and MMP2 …
Articular cartilage degeneration and bone adaptation due to lack of dystrophin in mice.
Dos Santos JF, Lazzarin MC, Baptista VIA, Quintana HT, Ribeiro DA, de Oliveira F. Dos Santos JF, et al. J Bone Miner Metab. 2022 Jan;40(1):29-39. doi: 10.1007/s00774-021-01270-x. Epub 2021 Sep 22. J Bone Miner Metab. 2022. PMID: 34549313
MATERIALS AND METHODS: Proximal femur of male 16-week-old Control and MDX mice were submitted to histological, morphometric (volume density of articular cartilage, compact bone, trabecular bone and bone marrow; articular cartilage layers area; articular carti …
MATERIALS AND METHODS: Proximal femur of male 16-week-old Control and MDX mice were submitted to histological, morphometric (volume density …
BMSC-HNC Interaction: Exploring Effects on Bone Integrity and Head and Neck Cancer Progression.
Eichberger J, Froschhammer D, Schulz D, Scholz KJ, Federlin M, Ebensberger H, Reichert TE, Ettl T, Bauer RJ. Eichberger J, et al. Int J Mol Sci. 2023 Sep 22;24(19):14417. doi: 10.3390/ijms241914417. Int J Mol Sci. 2023. PMID: 37833873 Free PMC article.
These activations corresponded with the release of collagenase enzymes, MMP9 and MMP2. To gain insights into bone resorption related to this interaction, bovine bone slices were used, supporting the growth of "heterogeneous spheroids" that contained both BMSC …
These activations corresponded with the release of collagenase enzymes, MMP9 and MMP2. To gain insights into bone resorption r …
Osteoblasts and osteocytes express MMP2 and -8 and TIMP1, -2, and -3 along with extracellular matrix molecules during appositional bone formation.
Hatori K, Sasano Y, Takahashi I, Kamakura S, Kagayama M, Sasaki K. Hatori K, et al. Anat Rec A Discov Mol Cell Evol Biol. 2004 Apr;277(2):262-71. doi: 10.1002/ar.a.20007. Anat Rec A Discov Mol Cell Evol Biol. 2004. PMID: 15052653 Free article.
Our previous studies suggested that a part of bone extracellular matrix (ECM) molecules are degraded and remodeled during embryonic bone formation. ...Osteoblasts and osteocytes may reorganize the ECM composition to mature the bone matrix in appositional b …
Our previous studies suggested that a part of bone extracellular matrix (ECM) molecules are degraded and remodeled during embryonic …
Different roles of matrix metalloproteinase 2 in osteolysis of skeletal dysplasia and bone metastasis (Review).
Li X, Jin L, Tan Y. Li X, et al. Mol Med Rep. 2021 Jan;23(1):70. doi: 10.3892/mmr.2020.11708. Epub 2020 Nov 25. Mol Med Rep. 2021. PMID: 33236155 Free PMC article. Review.
While MMP2 can degrade bone matrix, facilitate osteoclastogenesis and amplify various signaling pathways that enhance osteolysis in bone metastasis, its role in maintaining the number of bone cells, supporting osteocytic canalicular network formation a …
While MMP2 can degrade bone matrix, facilitate osteoclastogenesis and amplify various signaling pathways that enhance osteolys …
Bone marrow angiogenesis and plasma cell angiogenic and invasive potential in patients with active multiple myeloma.
Vacca A, Ribatti D, Roccaro AM, Ria R, Palermo L, Dammacco F. Vacca A, et al. Acta Haematol. 2001;106(4):162-9. doi: 10.1159/000046612. Acta Haematol. 2001. PMID: 11815713 Review.
A 5- to 6-fold larger area was found in patients with active MM compared to the other two groups. The conditioned medium (CM) of their bone marrow plasma cells stimulated endothelial cell proliferation and chemotaxis, monocyte chemotaxis and angiogenesis in vivo [chick emb …
A 5- to 6-fold larger area was found in patients with active MM compared to the other two groups. The conditioned medium (CM) of their bo …
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis.
Yang X, Zhang H, Wang J, Zhang Z, Li C. Yang X, et al. J Periodontal Res. 2015 Dec;50(6):748-57. doi: 10.1111/jre.12261. Epub 2015 Feb 3. J Periodontal Res. 2015. PMID: 25645818
BACKGROUND AND OBJECTIVE: Puerarin, the most abundant isoflavonoid in kudzu root, shows various bioactivities, including bone-sparing, anti-inflammatory and antiproteinase properties. This study aimed to evaluate the effects of puerarin in a rat model of ligature-induced p …
BACKGROUND AND OBJECTIVE: Puerarin, the most abundant isoflavonoid in kudzu root, shows various bioactivities, including bone-sparing …
Role of resistance training in bone macro and micro damages in an estrogen absence animal model.
Deriggi-Pisani GF, Stotzer US, Marqueti RC, Rodrigues MFC, Biffe BG, Silva KA, Fabricio V, Rosen CJ, Selistre-de-Araujo HS. Deriggi-Pisani GF, et al. Life Sci. 2023 Mar 15;317:121417. doi: 10.1016/j.lfs.2023.121417. Epub 2023 Jan 21. Life Sci. 2023. PMID: 36690246
AIMS: We evaluated the effects of resistance training (RT) on bone properties, morphology, and bone extracellular matrix (ECM) remodeling markers in an ovariectomy (OVX) rat model. ...On the other hand, RT did not decrease the number of bone adipocytes in the …
AIMS: We evaluated the effects of resistance training (RT) on bone properties, morphology, and bone extracellular matrix (ECM) …
Glycosaminoglycans influence enzyme activity of MMP2 and MMP2/TIMP3 complex formation - Insights at cellular and molecular level.
Ruiz-Gómez G, Vogel S, Möller S, Pisabarro MT, Hempel U. Ruiz-Gómez G, et al. Sci Rep. 2019 Mar 20;9(1):4905. doi: 10.1038/s41598-019-41355-2. Sci Rep. 2019. PMID: 30894640 Free PMC article.
Their activity is controlled by tissue inhibitors of metalloproteinases (TIMPs) and glycosaminoglycans (GAG). Here, we investigated the molecular interplay of MMP2 with different GAG (chondroitin sulfate, hyaluronan (HA), sulfated hyaluronan (SH) and heparin (HE)) and the …
Their activity is controlled by tissue inhibitors of metalloproteinases (TIMPs) and glycosaminoglycans (GAG). Here, we investigated the mole …
1,631 results